Interventions for acute non-arteritic central retinal artery occlusion (Cochrane Review)

A substantive amendment to this systematic review was last made on 26 November 2001. Cochrane reviews are regularly checked and updated if necessary.

Background: Acute central retinal artery occlusion occurs as a sudden interruption of the blood supply to the retina and results in an almost complete loss of vision in the affected eye. There is no generally agreed treatment regimen although a number of therapeutic interventions have been proposed.

Objectives: The objective of this review is to examine the effects of treatments used for acute non-arteritic central retinal artery occlusion.

Search strategy: We searched the Cochrane Controlled Trials Register - CENTRAL/CCTR, which contains the Cochrane Eyes and Vision Group specialised register (Cochrane Library Issue 4, 2001) , MEDLINE (1966 to August 2001) and EMBASE (1980 to September 2001). We searched the reference lists of relevant papers for trials.

Selection criteria: We included only randomised controlled trials in which one treatment aimed to re-establish blood supply to the retina in people with acute central retinal artery occlusion was compared to another treatment.

Data collection and analysis: Two reviewers independently assessed the search results for trials to be included in the review. Discrepancies were resolved by discussion.

Main results: We found no randomised controlled trials that met our inclusion criteria.

Reviewers' conclusions: There is currently not enough evidence to decide which, if any, interventions for acute non-arteritic central retinal artery occlusion would result in any beneficial or harmful effect. Well-designed randomised controlled trials are needed to establish the most effective treatment.

Citation: Fraser S, Siriwardena D. Interventions for acute non-arteritic central retinal artery occlusion (Cochrane Review). In: The Cochrane Library, Issue 3, 2003. Oxford: Update Software.

---

This is an abstract of a regularly updated, systematic review prepared and maintained by the Cochrane Collaboration. The full text of the review is available in The Cochrane Library (ISSN 1464-780X).

The Cochrane Library is designed and produced by Update Software Ltd.

Update Software Ltd, Summertown Pavilion, Middle Way, Oxford OX2 7LG, UK
(Tel:+44 1865 513902; Fax:+44 1865 516918)

File Reference: AB001989.htm